Task-correlated physiology reveals vascular-neural networks

We previously identified coupling of vascular-neural networks in BOLD fMRI data using simultaneous neural stimuli and hypercapnia paradigms. We repeat this experiment without a hypercapnic stimulus, observing robust changes in physiology time-locked to the neural tasks. These task-correlated physiologic effects are significantly more associated with the vascular networks identified previously, and identify an additional vascular network in bilateral motor cortices. Task-correlated physiology significantly affects multiple vascular networks and may mimic, spatially and temporally, neural network activations.

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