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Abstract #0229

MR Microscopy - Ultra-High Resolution 7T MRI in Pathologic Analysis of Resected Breast and Lymph Tissue

Brittany Dashevsky 1 , Krishna Juluru 1,2 , Timothy D'Alfonso 1 , Elizabeth Sutton 2 , Eric Aronowitz 1 , Ashley E. Giambrone 1 , and Doug Ballon 1

1 Weill Cornell Medical College, New York, NY, United States, 2 Memorial Sloan Kettering Cancer Center, New York, NY, United States

With 7T MR imaging of ex vivo fresh unfixed breast and lymph specimens at a spatial resolution of 60 x 60 x 90m, we identified characteristic features of both benign and malignant lesions compared with a light microscopy standard. Ultra-high resolution MRI offers a new tool in the management of breast cancer in ways that include defining pathology, delineating tumor margins, and optimizing specimens for pathologic processing. This tool promotes a novel approach to radiology - pathology collaboration and demonstrates the capabilities of 7T MR.

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