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Abstract #0338

Comparison of T2* correction methods for vertebral bone marrow fat quantification using chemical shift encoding-based water-fat imaging

Dimitrios C Karampinos 1 , Stefan Ruschke 1 , Michael Dieckmeyer 1 , Holger Eggers 2 , Hendrik Kooijman 3 , Ernst J Rummeny 1 , Jan S Bauer 4 , and Thomas Baum 1

1 Diagnostic and Interventional Radiology, Technische Universitt Mnchen, Munich, Germany, 2 Philips Research Laboratory, Hamburg, Germany, 3 Philips Healthcare, Hamburg, Germany, 4 Neuroradiology, Technische Universitt Mnchen, Munich, Germany

Spine fat fraction mapping is emerging with growing applications in osteoporosis and radiation therapy. Vertebral bone marrow is characterized by short T2* relaxation times. Therefore, vertebral bone marrow fat quantification using chemical shift encoding-based water-fat imaging needs to correct for T2* decay effects. The present study compares different approaches for T2* correction in water-fat imaging of vertebral bone marrow using single-voxel MRS as a reference standard. The advantage of a method correcting for a common T2′ and using a priori known T2 relaxation times for water and fat components is evaluated on the data from 26 young healthy volunteers.

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