Meeting Banner
Abstract #0421

Two-dimensional shaped voxel MRS in the human brain at 3 T

Patrick Waxmann 1 , Ralf Mekle 1 , Florian Schubert 1 , Andre Kuehne 2 , Tomasz Dawid Lindel 1 , Frank Seifert 1 , Oliver Speck 3 , and Bernd Ittermann 1

1 Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Berlin, Germany, 2 Medical University of Vienna, Vienna, Austria, 3 Otto-von-Guericke-University, Magdeburg, Germany

Spatially selective excitation (SSE) with parallel transmission was applied as a means to acquire signal from anatomy adapted voxels for in vivo 1H MR spectroscopy. A novel method to select spectroscopy voxels with two-dimensional arbitrary shapes was investigated. An on/off scheme with an adiabatic slice selective inversion pulse preceding a 2D-SSE pulse enabled rapid free induction decay acquisitions. High spatial fidelity of the SSE profiles on and off resonance was achieved. Metabolite concentrations in human brain determined with SHAVE were reliably quantified with LCModel (CRLB < 20 %) and did not deviate systematically from results acquired with a conventional SPECIAL sequence.

This abstract and the presentation materials are available to members only; a login is required.

Join Here