Encoding with Radiofrequency Spoiling, Equilibrium States and Inverse Problem for Parametric Mapping

Fast steady-state sequences often use RF spoiling to modulate contrast in MRI. The dynamic equilibrium depends on many parameters such as flip angle, longitudinal and transverse relaxations, and diffusion. Here it is shown that, extending the configuration state formalism, RF spoiling can be described as an encoding direction and equilibrium can be efficiently calculated with relaxation and diffusion. The inverse problem can then be solved to reconstruct associated parametric maps. Theory, practical implementation as well as proof-of-concept experiments on a clinical MRI system are given introducing new methods for efficient parametric mapping.

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