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Abstract #0479

Combined Functional and Metabolic Assessment of Brain Tumors using Hybrid MR-PET Imaging

Beatrice Sacconi 1 , Roy Raad 2 , Joon Lee 3 , Howard Fine 4 , John Golfinos 5 , Girish Manokar Fatterpekar 6 , Fernando Boada 7 , Kent Friedman 3 , James Babb 3 , and Rajan Jain 3

1 Radiological, Oncological and Anatomopathological Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Rome, Italy, 2 Radiology, NYU School of medicine, New York, New York, United States, 3 Radiology, NYU School of Medicine, New York, New York, United States, 4 Neuro-oncology, NYU Langone Medical Center, New York, New York, United States, 5 Neurosurgery, NYU Langone Medical Center, New York, New York, United States, 6 Radiology, NYU Langone Medical Center, New York, New York, United States, 7 Neurosurgery, Psichiatry and Radiology, NYU Langone Medical Center, New York, New York, United States

Combined functional (MR perfusion) and metabolic (FDG-PET) assessment of brain tumors using hybrid MR-PET provides good accuracy and complimentary information about brain tumors which could be useful as a diagnostic and surveillance tool. PWI and tumor blood volume estimation performs better as compared to FDG uptake assessment in differentiating low versus high-grade tumors as well as in differentiating recurrent tumor from treatment/radiation induced necrosis in previously treated patients in a concurrent hybrid setting.

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