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Abstract #0501

Actual Flip Angle Imaging to Improve T1 Measurement for Short T2 Tissues

Misung Han 1 , Peder EZ Larson 1 , Roland Krug 1 , and Viola Rieke 1

1 Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States

A variable flip angle method is a rapid T 1 mapping method by exploiting steady-state signals at multiple flip angles. When combined with ultrashort echo-time imaging, T 1 measurement for short T 2 * tissues is also possible. However, flip angle errors due to miscalibration or B 1 inhomogeneities, and T 2 * relaxation effects during RF excitation can degrade the accuracy of T 1 quantification. In this work, we propose the use of the actual flip imaging technique to correct flip angles to improve T 1 measurement for short T 2 tissues. Ex vivo study on bovine cortical bone and in vivo study on the Achilles tendon are presented.

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