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Abstract #0533

Quantification of liver perfusion using multi-delay Pseudo-Continuous Arterial Spin Labeling

Xinlei Pan 1 , Robert Smith 2 , Mayank Jog 2 , Tianyi Qian 3 , Holden H Wu 2 , Kyunghyun Sung 2 , Kuncheng Li 4 , Kui Ying 5 , and Danny JJ Wang 2

1 Department of Biomedical Engineering, Tsinghua University, Beijing, Beijing, China, 2 Department of Bioengineering, UCLA, CA, United States, 3 Siemens Healthcare, MR Collaboration NE Asia, Beijing, China, 4 Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing, China, 5 Department of Engineering Physics, Tsinghua University, Beijing, China

This study tested the feasibility of quantitative liver perfusion measurements using a multi-delay pseudo-continuous ASL (pCASL) protocol that selectively labels the hepatic artery and hepatic portal vein respectively. Estimated mean blood flow of hepatic artery labeled (4414 ml/100ml/min) and hepatic portal vein labeled (1409 ml/100ml/min) as well as the corresponding transit times (1020396,1892164ms) showed good accordance with the literature. The capability of non-invasively and selectively labeling the hepatic artery and portal vein is a unique strength of pCASL for quantitative liver perfusion imaging.

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