Abstract #0533
Quantification of liver perfusion using multi-delay Pseudo-Continuous Arterial Spin Labeling
Xinlei Pan 1 , Robert Smith 2 , Mayank Jog 2 , Tianyi Qian 3 , Holden H Wu 2 , Kyunghyun Sung 2 , Kuncheng Li 4 , Kui Ying 5 , and Danny JJ Wang 2
1
Department of Biomedical Engineering,
Tsinghua University, Beijing, Beijing, China,
2
Department
of Bioengineering, UCLA, CA, United States,
3
Siemens
Healthcare, MR Collaboration NE Asia, Beijing, China,
4
Department
of Radiology, Xuanwu Hospital of Capital Medical
University, Beijing, China,
5
Department
of Engineering Physics, Tsinghua University, Beijing,
China
This study tested the feasibility of quantitative liver
perfusion measurements using a multi-delay
pseudo-continuous ASL (pCASL) protocol that selectively
labels the hepatic artery and hepatic portal vein
respectively. Estimated mean blood flow of hepatic
artery labeled (4414 ml/100ml/min) and hepatic portal
vein labeled (1409 ml/100ml/min) as well as the
corresponding transit times (1020396,1892164ms) showed
good accordance with the literature. The capability of
non-invasively and selectively labeling the hepatic
artery and portal vein is a unique strength of pCASL for
quantitative liver perfusion imaging.
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