Abstract #0540
Large intramuscular vessel artifact in ASL: effect on calf muscle perfusion measurements and a velocity-selective solution
Jeff L Zhang 1 , Christopher J Hanrahan 1 , Jason Mendes 1 , Gwenael Layec 2 , Corey Hart 2 , Kristi Carlston 1 , Michelle Mueller 3 , Russell S Richardson 2 , and Vivian S Lee 1
1
Radiology, University of Utah, Salt Lake
City, Utah, United States,
2
Division
of Geriatrics, University of Utah, Utah, United States,
3
Vascular
Surgery, University of Utah, Utah, United States
Capable of measuring perfusion rapidly, ASL is suitable
for monitoring muscle perfusion during exercise
recovery. However, ASL estimated perfusion could be
severely erroneous for tissue voxels containing large
blood vessels. Inclusion of large-vessel voxels in a
muscle ROI could change the magnitude and the temporal
pattern of the averaged perfusion dramatically. In this
study, we studied ASL signals of blood vessel simulated
by a flow phantom, and using the obtained
velocity-perfusion relationship, developed a velocity
selective method for excluding the large-vessel voxels.
The method was shown to be effective for our healthy
subjects, and improved the perfusion accuracy.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
