Abstract #0785
Balanced Steady State Free Precession (bSSFP) from an effective field perspective: application to the detection of exchange (bSSFPX)
Shu Zhang 1 , Zheng Liu 2 , Robert E. Lenkinski 1,3 , and Elena Vinogradov 1,3
1
Radiology, UT Southwestern Medical Center,
Dallas, TX, United States,
2
Advanced
Imaging Research Center, Oregon Health & Science
University, Portland, OR, United States,
3
Advanced
Imaging Research Center, UT Southwestern Medical Center,
Dallas, TX, United States
In this work we demonstrate that pulses of bSSFP
generate an effective RF field akin to the
saturation/spin-lock RF train. Thus, bSSFP and
CEST/T1rho experiments are completely analogous. While
in CEST the Z component of magnetization is observed,
here we are focusing on the XY component. Analysis of
the off-resonance frequency dependence of bSSFP profile
(bSSFPX) provides information similar to CEST. We
present a theoretical treatment, confirmation by
simulation, and demonstrate the proof-of-principle with
an image of an exchanging agent acquired using this
bSSFPX approach. This method may lead to fast
acquisition and quantification approaches.
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