Meeting Banner
Abstract #0793

Intra and Inter-subject Reproducibility of Arterial Transit Time

Tracy Ssali 1,2 , Udunna C Anazodo 1,2 , Mahsa Shokouhi 1 , Bradley J MacIntosh 3 , and Keith St Lawrence 1,2

1 Laswon Health Research Institute, London, Ontario, Canada, 2 University of Western Ontario, London, Ontario, Canada, 3 Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

It is known that knowledge of the arterial transit time (ATT) is essential for CBF quantification; however, typically ATT imaging is time consuming. The aim of this study was to assess intra- and inter-subject reproducibility of ATT. Across sessions and subjects, the voxel-wise GM CV were 6.0% and 10.0%, respectively. Variance in mean GM ATT inter-subject was 44.7ms (CV=5.4%) and 5.9ms (CV=0.7%) inter-session. The low variance demonstrates the stability of ATT measurements in young healthy individuals. Next, would be to assess reproducibility of ATT in older subject groups and patient populations with cerebral pathology where perfusion characteristics have greater variability.

This abstract and the presentation materials are available to members only; a login is required.

Join Here