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Abstract #0800

Carbohydrate requirements during intermittent high intensity exercise compared to continuous moderate intensity exercise in individuals with type 1 diabetes

Tania Buehler 1 , Lia Bally 2 , Ayse Sila Dokumaci 1 , Christoph Stettler 2 , and Chris Boesch 1

1 Depts. Radiology and Clinical Research, University Bern, Bern, Switzerland, 2 Division of Endocrinology, Diabetes and Clinical Nutrition, Inselspital Bern, Bern, Switzerland

The need to administer exogenous insulin in type 1 diabetes mellitus (T1DM) subjects generally increases the risk of exercise-related hypoglycemia. A better understanding of exercise-associated fuel metabolism is essential to develop strategies to improve glucose stability. In this study two types of exercise protocols (moderate (CONT) and high intermittent intensity (IHE)) were performed in T1DM subjects to evaluate glucose requirements and hepatic and myocellular glycogen consumption during the two different exercise interventions. The IHE protocol provides a feasible strategy to reduce glucose requirements during the exercise. This is correlated with an increased consumption of hepatic glycogen.

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