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Abstract #0835

Neural Correlates of Phonological Processing in 4-6 year olds

Andrea S. Miele 1 , Holly Dirks 2 , Dannielle John Whiley 2 , Terry Harrison-Goldman 1 , Viren D'Sa 3 , and Sean Deoni 2,4

1 Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island, United States, 2 Advanced Baby Imaging Laboratory, Brown University, Providence, Rhode Island, United States, 3 Pediatrics, Neurodevelopmental Center, MHRI, Pawtucket, Rhode Island, United States, 4 Pediatric Radiology, Children's Hospital Colorado, Colorado, United States

Phonological processing development is considered essential for reading acquisition. Deficient phonological awareness is considered a core feature of the specific learning disability, dyslexia. Despite being neurobiological in origin, the underlying mechanisms that lead to deficits in phonological processing and dyslexia remain elusive. Results support a positive relationship between myelin content and performance on a measure of phonological awareness in very young children. Underlying aspects of phonological awareness appear related to distinct WM correlates not only in the frontal subcortical system but also in the temporal lobe, suggesting involvement of auditory and visual processing systems as well.

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