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Abstract #0843

The Effect of Parallel Radiofrequency Transmission on Arterial Input Function Selection in 3T DCE-MRI of Prostate Cancer

Hatim Chafi 1 , Saba N Elias 2 , Huyen T Nguyen 2 , Harry T Friel 3 , Michael V Knopp 2 , BeiBei Guo 4 , Steven B Heymsfield 5 , and Guang Jia 1

1 Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA, United States, 2 Department of Radiology, The Ohio State University, Columbus, Ohio, United States, 3 Clinical Science Operations, Philips Healthcare, Highland Heights, Ohio, United States, 4 Department of Experimental Statistics, Louisiana State University, Baton Rouge, Louisiana, United States, 5 Metabolism - Body Composition, Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States

18 prostate cancer patients underwent DCE-MRI scans on a 3T scanner) using a single channel RF transmit Q-body and 32-channel phased-array surface coils, while 21 patients were imaged on the same scanner with a parallel RF transmission upgrade. Comparison of baseline signal and signal enhancement in the left and right femoral arteries, indicates that baseline signals and signal enhancement are significantly more symmetrical. High field (3.0 T) MRI scanners equipped with multiple-channel parallel RF transmission enhances the symmetry of arterial input function in femoral arteries resulting in more consistent and homogeneous quantitative pharmacokinetic modeling in DCE-MRI of prostate cancer.

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