Prognostic Value of MR Parameters Obtained Prior to the Initiation of Neoadjuvant Chemotherapy: A Comparison with Traditinal Prognostic Indicators
Martin D Pickles 1 , Peter Gibbs 1 , Martin Lowry 1 , and Lindsay W Turnbull 1
Centre for Magnetic Resonance
Investigations, Hull York Medical School at University
of Hull, Hull, East Yorkshire, United Kingdom
The aims of this study were to determine if any
associations exist between MR parameters and survival
intervals; and to compare the prognostic value of MR
parameters against traditional survival indicators.
Size, vascular, texture and shape parameters were
obtained from dynamic breast MR datasets in 81
individuals. Survival analysis demonstrated that MR
parameters (textural and shape) can provide independent
prognostic information that can complement traditional
prognostic indicators. Further it seems that MR
parameters may have a role to play in treatment
stratification for breast cancer patients since these
survival associations are evident prior to the
initiation of neoadjuvant chemotherapy treatment.
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