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Abstract #0889

Prognostic Value of MR Parameters Obtained Prior to the Initiation of Neoadjuvant Chemotherapy: A Comparison with Traditinal Prognostic Indicators

Martin D Pickles 1 , Peter Gibbs 1 , Martin Lowry 1 , and Lindsay W Turnbull 1

1 Centre for Magnetic Resonance Investigations, Hull York Medical School at University of Hull, Hull, East Yorkshire, United Kingdom

The aims of this study were to determine if any associations exist between MR parameters and survival intervals; and to compare the prognostic value of MR parameters against traditional survival indicators. Size, vascular, texture and shape parameters were obtained from dynamic breast MR datasets in 81 individuals. Survival analysis demonstrated that MR parameters (textural and shape) can provide independent prognostic information that can complement traditional prognostic indicators. Further it seems that MR parameters may have a role to play in treatment stratification for breast cancer patients since these survival associations are evident prior to the initiation of neoadjuvant chemotherapy treatment.

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