Abstract #0896
Neurochemical and BOLD Responses in Activated Blob and Interblob Neuronal Populations Measured in the Human Visual Cortex at 7T
Petr Bednarik 1,2 , Ivan Tkac 1 , Federico Giove 3,4 , Dinesh Deelchand 1 , Lynn Eberly 1 , Felipe Barreto 1,5 , and Silvia Mangia 1
1
University of Minnesota, Minneapolis, MN,
United States,
2
Central
European Institute of Technology, Masaryk University,
Brno, Czech Republic,
3
MARBILab c/o Fondazione
Santa Lucia, "Enrico Fermi" Centre, Rome, Italy,
4
",
Department of Physics - G1 Group, University of Rome "La
Sapienza", Rome, Italy,
5
Physics
Department, University of Sao Paulo, Sao Paulo, Brazil
Different functional metabolisms might be expected in
selectively activated blob and interblob neuronal
populations due to different cytochrome-oxidase
contents. Here we acquired fMRI and fMRS data during
chromatic and achromatic visual stimuli, which
selectively activate blob and interblob neurons,
respectively. Neurochemical and fMRI-BOLD responses were
measured from 12 subjects, each scanned twice. We
observed robust BOLD-fMRI signals as well as functional
changes in concentration of Glu, Lac, Asp and Glc for
both stimuli. No significant differences in
neurochemical and BOLD responses between chromatic and
achromatic stimuli were found, consistent with equal
aerobic responses in blob and interblob neuronal
populations.
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