Abstract #0944
Two-compartment T2 Decay for Prostate Cancer Diagnosis
Shiyang Wang 1 , Harsh Agarwal 2 , Gregory S. Karczmar 1 , and Aytek Oto 1
1
Radiology, University of Chicago, Chicago,
IL, United States,
2
Clinical
Research Development, Philips Research North America,
Briarcliff, Manor, NY, United States
Accurate modeling of T2 decay in prostate may improve
the prostate cancer detection. Glandular structure of
prostate suggests multi-compartment T2 decay of
prostate. In this manuscript multi-echo TSE MRI over
TE=24 to 396msec was acquired and fitted to mono and
bi-exponential T2 decay models. Individual parameters
from mono and bi exponential fitting were able to show
significant difference between cancer and normal
prostate tissue. An accelerated ME-TSE is repeated twice
and compared with un-accelerated ME-TSE MRI showed that
accelerated ME-TSE is accurate but is less precise may
be due to lower SNR.
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