Abstract #0992
High-Resolution 1 H-MRSI of the Brain using Short-TE SPICE
Chao Ma 1 , Fan Lam 1,2 , Qiang Ning 1,2 , Curtis L. Johnson 1 , and Zhi-Pei Liang 1,2
1
Beckman Institute, University of Illinois at
Urbana-Champaign, Urbana, Illinois, United States,
2
Department
of Electrical and Computer Engineering, University of
Illinois at Urbana-Champaign, Illinois, United States
SPICE (SPectroscopic Imaging by exploiting
spatiospectral CorrElation) is emerging as a powerful
tool for high-resolution spectroscopic imaging of the
brain. As voxel size is getting smaller at higher
resolution, further improvement of signal-to-noise ratio
(SNR) becomes essential, especially with sparse sampling
in (k,t)-space. This work presents a novel data
acquisition and processing method to enable short-TE
SPICE for high-resolution 1H-MRSI of the brain. In vivo
experimental results show that the proposed method can
achieve 2mm in-plane resolution in good SNR with a TE of
20ms in a 30min scan.
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