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Abstract #0997

Contrast Generation with a Novel Adiabatic On-Resonance Magnetization Transfer Preparation (MT-Prep)

Wolfgang G Rehwald 1 , David C Wendell 2 , Elizabeth R Jenista 2 , Han W Kim 2 , Enn-Ling Chen 2 , Igor Klem 2 , and Raymond J Kim 2

1 Siemens Healthcare, Durham, NC, United States, 2 Cardiology, Duke University Medical School, Durham, North Carolina, United States

Magnetization transfer contrast could be a clinically and technically advantageous alternative to T2-contrast. It would be useful for imaging edema and creating tissue-blood contrast, if its energy and power requirements did not exceed the capabilities of most clinical MRI scanners. To address this issue, we designed an efficient adiabatic on-resonance MT module that imparts significant MT-weighting while remaining within the energy and power constraints of most clinical MRI scanners. In ten cardiac patients, we compared this module to standard high-power off-resonance MT preparation and established its image quality and contrast equivalence while only requiring a fraction of its energy.

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