Abstract #1059
Viscoelasticity of Subcortical Gray Matter Structures
Curtis L Johnson 1 , Hillary Schwarb 1 , Matthew DJ McGarry 2 , Bradley P Sutton 1 , and Neal J Cohen 1
1
Beckman Institute for Advanced Science and
Technology, University of Illinois at Urbana-Champaign,
Urbana, IL, United States,
2
Thayer
School of Engineering, Dartmouth College, Hanover, NH,
United States
The mechanical properties of specific neuroanatomical
regions estimated with magnetic resonance elastography
(MRE) have shown promise in reflecting the presence of
disease. In this work, we introduce a high-resolution
MRE method for examining subcortical gray matter
structures that is specifically designed to overcome
issues arising from inadequate spatial resolution and
proximity to cerebrospinal fluid. In a group of healthy
young participants, we find differences in
viscoelasticity between the hippocampus, thalamus, and
putamen. Ultimately, such measurements may be critical
for improved evaluation of aging and neurological
disease by studying regions linked to functional
decline.
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