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Abstract #1136

Evaluation of lipid composition in patients with benign tissue and cancer using multiple gradient echo MRI

Melanie Freed 1,2 , Pippa Storey 1,2 , Alana Amarosa Lewin 1 , Melanie Moccaldi 1 , Linda Moy 1 , and Sungheon G. Kim 1,2

1 Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, NY, United States, 2 Center for Advanced Imaging Innovation and Research (CAI2R), Dept. Radiology, NYU School of Medicine, New York, NY, United States

Obesity is a known risk factor for developing breast cancer. So far, there has not been a comprehensive study comparing the lipid composition in the breast for patients with benign tissue and cancer. Part of the reason this remains a challenge is the lack of methods to non-invasively investigate lipid composition in breast tissue. We use a multiple gradient echo acquisition to rapidly acquire lipid spectral maps in the breast. These data suggest that for post-menopausal women, lower monounsaturated and higher saturated fatty acids may be related to breast cancer development.

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