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Abstract #1271

fMRI Measures of the Dorsal Visual Cortex Correlates with Behavioral Performance and Cortical Thickness

Tanya Poppe 1 , Myra Leung 1 , Anna Tottman 2 , Jane Alsweiler 3 , Frank Bloomfield 2 , Jane Harding 2 , and Ben Thompson 1,4

1 Department of Optometry and Vision Science, University of Auckland, Auckland, New Zealand, 2 Liggins Institute, University of Auckland, Auckland, New Zealand, 3 Department of Paediatrics: Child and Youth Health, University of Auckland, Auckland, New Zealand, 4 Department of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada

This study revealed that a higher order visual pathway, thought to be sensitive to abnormal neurodevelopment, could be assessed using fMRI in seven-year-old children. Furthermore, the fMRI results were correlated with cortical thickness and performance of a visual task outside of the scanner environment. These findings are consistent with electrophysiology (in non-human primates), electroencephalography (EEG), and magnetoencephalography (MEG) studies in adults. fMRI of visual brain areas may provide a sensitive biomarker for abnormal neurodevelopment in children.

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