Abstract #1289
Age Related Changes of the Interrelationships of White Matter in Autism Spectrum Disorder
Douglas Dean 1 , Brittany Travers 1 , Erin Bigler 2 , Molly Prigge 3 , Alyson Froehlich 3 , Nicholas Lange 4 , Janet Lainhart 1 , and Andrew Alexander 1
1
Waisman Center, University of
Wisconsin-Madison, Madison, WI, United States,
2
Brigham
Young University, Provo, UT, United States,
3
University
of Utah, Salt Lake City, UT, United States,
4
Harvard
School of Medicine and McLean Hospital, Belmont, MA,
United States
Brain imaging findings in children with autism spectrum
disorder (ASD) suggest the disorder is associated with
altered brain development and disrupted structural and
functional brain connectivity," which implies atypical
white matter microstructure in at least some parts of
the brain in ASD. However, it is unclear how homogeneous
the structural organization of the white matter
microstructure is within the brains of individuals with
ASD at different ages. In this work, we examine
correlations among the microstructure of different white
matter tracts in childhood and adulthood in ASD compared
to typical development.
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