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Abstract #1313

T 2 estimation of downfield metabolites in human brain at 7T

Nicole D. Fichtner 1,2 , Anke Henning 2,3 , Niklaus Zoelch 2 , Chris Boesch 1 , and Roland Kreis 1

1 Depts. Radiology and Clinical Research, University Bern, Bern, Switzerland, 2 Institute for Biomedical Engineering, UZH and ETH Zurich, Zurich, Switzerland, 3 Max Planck Institute for Biological Cybernetics, Tuebingen, Germany

The upfield part of the spectrum has thus far been well-characterized using magnetic resonance spectroscopy; however, the downfield part at 5-10ppm remains less so, particularly in humans. This work aims to improve metabolite characterization by calculating the T 2 s of peaks downfield in grey matter at 7 T. We fitted downfield spectra to a heuristic model and obtained T 2 s for several peaks of interest; the T 2 s are all fairly similar, but significantly shorter than those reported for upfield peaks in the brain, which are approximately 70ms or longer depending on the structure.

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