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Abstract #1324

Consistency of 1 H-MRS in the putamen of healthy adult controls over six years.

Bretta Russell-Schulz 1 , Terri L Petkau 2 , Blair R Leavitt 2,3 , and Alex L MacKay 1,4

1 Radiology, University of British Columbia, Vancouver, BC, Canada, 2 Centre for Molecular Medicine and Therapeutics, Child & Family Research Institute, Vancouver, BC, Canada, 3 Medical Genetics, University of British Columbia, Vancouver, BC, Canada, 4 Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada

Here we present 1 H-MRS results for the putamen over 6 years, 7 timepoints for healthy adult controls. There were no significant differences in the metabolite concentrations over the 7 visits, showing the validity of using these controls to compare to pathological data of the Huntington Disease over this timescale. The potential effects of age on metabolite concentration were also examined.

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