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Abstract #1335

Separation of VLF fluctuations from periodic cardiorespiratory noise with critically sampled magnetic resonance encephalography.

Vesa Kiviniemi 1 , Xindi Wang 2 , Vesa Korhonen 1 , Tuija Keinnen 3 , Yu-Feng Zang 4 , Pierre LeVan 5 , and Shella Keilholz 6

1 Diagnostic Radiology, MRC, Oulu University Hospital, Oulu, Oulu, Finland, 2 Beijing Normal University, Beijing, China, 3 Clinical Neurophysiology, MRC, Oulu University Hospital, Oulu, Oulu, Finland, 4 Hangzhou Normal University, Hangzhou, China, 5 University of Freiburg, Freiburg, Germany, 6 Emory University, Atlanta, Georgia, United States

We imaged whole brain with magnetic resonance encpehalography using a 100 ms TR under-sampled k-space trajectory. This critical sampling enabled separation of cardiac pulse and respiratory effects from very low frequency BOLD signal sources. We show that physiological noise has a unique spatiotemporal patterns of noise propagation pattern throughout the brain. The results suggest that conventional averaged external estimates of physiological noise need to be replaced by critically sampled brain data.

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