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Abstract #1379

The Use of Magnetic Resonance Spectroscopy in the Evaluation of Epilepsy in Pediatric Patients

Marisa Blitstein 1 , Sandra Rincon 1 , Paul Caruso 1 , Ronald Thibert 2 , Ramon Gilberto Gonzalez 1,3 , and Eva-Maria Ratai 1,3

1 Department of Radiology, Neuroradiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 2 Neurology / Pediatric Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 3 A. A. Martinos Center for Biomedical Imaging, MA, United States

The purpose of our study was to retrospectively evaluate MRI, MRS, and clinical data to determine how often MRS added information to conventional MRI for evaluation of seizure in pediatric patients. A database search between 1/1/2011 and 12/31/2013 to identify patients <18 years old with both MRI and MRS for evaluation of seizure resulted in 241 cases. In our series, MRS yielded additional information for 40% (96/241) of all patients. The largest subsets of patients that had MRS exams yielding additional information were patients with hypoxic ischemic injury, distinguishing dysplasia from neoplasm, and prompting metabolic or genetics workup.

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