Abstract #1385
Optimizing gray-matter white-matter contrast on three-dimensional double inversion recovery MRI using patient-specific inversion times
Refaat E Gabr 1 , Xiaojun Sun 1 , Amol S Pednekar 2 , and Ponnada A Narayana 1
1
Department of Diagnostic and Interventional
Imaging, The University of Texas Health Science Center
at Houston, Houston, TX, United States,
2
Philips
Healthcare, Cleveland, OK, United States
Optimization of double inversion recovery protocols is
usually performed based on the expected relaxation times
in a certain class of patients. Natural and
disease-related variations in tissue relaxation cause
inconsistent tissue suppression and suboptimal contrast
across studies. In this work we explore a
patient-specific approach for maximizing tissue contrast
based on fast relaxation scout and pseudo-real-time
image processing pipeline integrated into a clinical
scanner. Experiments in healthy subjects show that
subject-specific optimizations produce large gains in
tissue contrast without scan time penalty, with only one
minute of processing time.
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