Central sulcus and pericentral cortical changes in multiple sclerosis

Cortical atrophy is a key imaging hallmark of multiple sclerosis (MS). The aim of this study was to investigate the differences in sulcal volume, width and depth of the central sulcus as well as pericentral cortical gray matter (Pc-CGM) thickness between MS patients and healthy controls. Results showed increased volume and width of the central sulcus and decreased Pc-CGM in patients. The sulcal changes correlated with the local atrophy measure of Pc-CGM in patients. Since CS metrics are correlated with clinical disability measure, there is potential to use them as quantitative markers of progression.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.