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Abstract #1412

A Comparative Study of Diffuse and Focal Traumatic Brain Injury using Multi-echo Susceptibility Weighted Imaging in Rodent Model

Sanjay Verma 1 , Bhanu Prakash KN 1 , Sankar Seramani 1 , Enci Mary Kan 2 , Kian Chye Ng 2 , Mui Hong Tan 2 , Jia Lu 2 , and S Sendhil Velan 1

1 Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore, 2 Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore

Traumatic brain injury (TBI) is a serious and global public health issue. Focal and diffuse are the two ways to classify brain injuries. Multi-echo Susceptibility weighted imaging provides phase with better SNR and CNR and R2*, making it a sensitive technique for brain injury. A comparative study of focal (fluid percussion injury) and diffuse (open field blast) TBI using multi echo SWI has been made in this study.

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