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Abstract #1415

DTI predicts functional deficit in professional boxers.

Wanyong Shin 1 , Blessy Mathew 1 , Katherine Koenig 1 , Banks Sarah 2 , Mark J Lowe 1 , Michael Phillips 1 , Michael Modic 3 , and Charles Bernick 2

1 Imaging Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States, 2 Lou Ruvo Center for Brain Health, Cleveland Clinic Foundatoin, Las Vegas, Nervada, United States, 3 Neurological Institute, Cleveland Clinic Foundatoin, Cleveland, Ohio, United States

The Professional Fighters Brain Health Study (PFBHS) is a longitudinal study to monitor a cohort of active professional fighters including boxers and mixed martial arts (MMA) fighters annually over 4 years. In this study, we analyzed data from the baseline visits of 305 male boxers and MMA fighters, and ran voxelwise DTI group analysis to investigate the correlation between whole brain DTI findings and results from a computerized cognitive test battery (CNS Vital Signs). We found that transverse diffusivity in white matter is highly correlated with CNS vital measures in boxers, but not in MMA fighters. This finding might be due to the increased number of head blows in boxing, compared to MMA.

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