Abstract #1435
Test-retest reproducibility of BOLD-CVR measures in children using a computer-controlled CO 2 challenge
Jackie Leung 1 , Junseok Kim 2 , and Andrea Kassner 1,3
1
The Hospital for Sick Children, Toronto,
Ontario, Canada,
2
Institute
of Medical Science, University of Toronto, Toronto,
Ontario, Canada,
3
Medical
Imaging, University of Toronto, Toronto, Ontario, Canada
Cerebrovascular reactivity (CVR) is a form of a
cerebrovascular 'stress test' that offers insight into
the function of cerebrovasculature and has shown
applicability in the clinical assessment cerebrovascular
disease. Good reproducibility has previously been shown
in adults using blood-oxygen level-dependent (BOLD) MRI
measures in combination with a model-free prospective
end-tidal targeting (MPET) system. However,
reproducibility in children using this method has not
yet been established. Our study shows good within-day
and between-day reproducibility of BOLD-CVR measures
using the MPET that is comparable to the adult data.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
