Validating a power relationship between cerebral blood volume and cerebral blood flow
Jie Huang 1
Department of Radiology, Michigan State
University, East Lansing, MI, United States
Cerebral blood volume (CBV) is related with cerebral
blood flow (CBF), and knowing this relationship may play
an important role in quantitative BOLD-fMRI studies. A
recent MRI study reports a sex-dependent CBV-CBF power
relationship in the human visual cortex. In this study,
we computed CBV for each CBF using the power function
and the CBF values at both rest and activation states.
Comparisons of these computed CBV values with their
corresponding measured CBV values for each sex revealed
significant differences (max P=0.0014), suggesting the
CBV-CBF relationship may not be best characterized by
the power function.
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