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Abstract #1478

Static Lung Volumes Assessed on MRI with Spirometry Control in Comparison to Body-Plethysmography

Yanping Sun 1 , Christian M Lo Cascio 1 , Firas S Ahmed 2 , Meghaq A Parikh 1 , Yongqiang Tan 2 , Binsheng Zhao 2 , Robert C Basner 1 , Paul Enright 3 , Martin R Prince 4 , and R Graham Barr 1

1 Medicine, Columbia University Medical Center, New York, NY, United States, 2 Radiology, Columbia University Medical Center, New York, NY, United States, 3 Medicine, University of Arizona, Tucson, AZ, United States, 4 Radiology, Cornell University Medical Center, New York, NY, United States

Lung volumes such as total lung capacity (TLC), functional residual capacity (FRC) and residual volume (RV) are used to quantify restriction, hyperinflation and gas trapping. Absolute static lung volumes are often measured using a body-plethysmograph; however, measurements are indirect, derived based upon Boyles Law, and can be imprecise. We tested the reproducibility of lung volumes measured directly on MRI with concomitant spirometry control and compared to body-plethysmograph measurements. TLC and RV measured by MRI met ATS/ERS criteria for reproducibility, as did TLC and FRC by plethysmography . TLC on MRI and plethysmography were highly correlated (r=0.98; P<0.001).

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