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Abstract #1499

Evaluation of Radiation-induced Lung Injury by Hyperpolarized Xenon

Zhiying Zhang 1 , Haidong Li 1 , Xianping Sun 1 , Xiuchao Zhao 1 , Chaohui Ye 1 , and Xin Zhou 1

1 National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, China

Our study shows that hyperpolarized 129Xe MRI can noninvasively detect the RILI. By using the CSSR sequence and the model of xenon exchange to detect the exchange time in blood and tissue, 129Xe MRI appears to be able to quantitatively evaluate and monitor the changes of lung functions, which is in agreement with the pathological results.

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