Abstract #1500
Multi nuclear 3D multiple breath washout imaging with 3 He and 129 Xe using a dual tuned coil
Felix C Horn 1 , Madhwesha Rao 1 , Neil J Stewart 1 , Helen Marshall 1 , Juan Parra-Robles 1 , and Jim M Wild 1
1
Academic Radiology, University of Sheffield,
Sheffield, United Kingdom
A recently introduced method describes 3D multiple
breath washout imaging using hyperpolarized gas MRI.
This preliminary study presents a methodology for
multiple breath washout imaging with 129-Xe and 3-He
using steady-state (bSSFP) imaging and a dual-tuned
radiofrequency coil. Comparable functional information
was derived from MBW-I datasets from both nuclei, with
similar ventilation heterogeneity exhibited by each,
despite the intrinsically different physical properties
of the two nuclei. In future work, it may be possible to
identify sensitivity differences in MBW-I with 3-He and
129-Xe to different physiological processes symptomatic
of lung disease.
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