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Abstract #1501

Comparing Pulmonary MRI using Inert Fluorinated Gases and Hyperpolarized 3 He: Is 19 F MRI Good Enough?

Marcus J. Couch 1,2 , Iain K. Ball 2 , Tao Li 2 , Matthew S. Fox 3,4 , Birubi Biman 5,6 , and Mitchell S. Albert 1,2

1 Lakehead University, Thunder Bay, Ontario, Canada, 2 Thunder Bay Regional Research Institute, Thunder Bay, Ontario, Canada, 3 Robarts Research Institute, London, Ontario, Canada, 4 Department of Medical Biophysics, Western University, London, Ontario, Canada, 5 Thunder Bay Regional Health Sciences Centre, Thunder Bay, Ontario, Canada, 6 Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada

19 F MRI of the lungs is a new pulmonary imaging modality that uses inhaled inert fluorinated gases as a signal source to acquire images of the lungs. The purpose of this study was to perform a direct comparison between inert fluorinated gas and hyperpolarized 3 He MR lung imaging in the same subjects. This preliminary study demonstrates the potential of using inert fluorinated gas MRI to visualize the distribution of ventilation in human lungs, and this technique may yield meaningful functional information that is similar to hyperpolarized 3 He MRI.

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