Abstract #1508
Postprandial Hepatic Glycogen Levels following a Low v High Glycaemic Index Breakfast: A 13 C MRS Study
S Bawden 1,2 , MC Stephenson 3 , K Hunter 4 , M Taylor 5 , L Marciani 1 , PG Morris 2 , IA Macdonald 6 , GP Aithal 1 , and PA Gowland 2
1
NIHR Nottingham Digestive Diseases
Biomedical Research Unit, Nottingham University
Hospitals NHS Trust and University of Nottingham,
Nottingham, United Kingdom,
2
Sir
Peter Mansfield Imaging Centre, University of
Nottingham, Nottingham, United Kingdom,
3
Agency
for Science, Technology and Research, Singapore,
4
Unilever
Discover, Bedfordshire, United Kingdom,
5
Faculty
of Human Nutrition, University of Nottingham, United
Kingdom,
6
School
of Life Sciences, University of Nottingham, United
Kingdom
Natural abundance
13
C
MRS measurements of liver glycogen levels were acquired
from 8 healthy males using a multinuclear surface coil
with proton decoupling in a randomized cross over study
comparing the postprandial effects of a calorie and
macronutrient matched high v low glycaemic index test
breakfast. The results from this study showed an
immediate increase from fasted levels following both
meals which began to decline from 180 minutes for the
low GI meal but continued to increase for 300 minutes
for the high GI meal
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