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Abstract #1511

The role of IVIM and Chemical Shift imaging in detecting early hepatic complications of Diabetes Mellitus Type 2

Sonia Isabel Goncalves 1,2 , Filipe Caseiro Alves 2,3 , and Miguel Castelo Branco 1,2

1 Institute for Biomedical Imaging and Life Sciences, Coimbra, Coimbra, Portugal, 2 Faculty of Medicine, University of Coimbra, Coimbra, Coimbra, Portugal, 3 Radiology, University Hospital Coimbra, Coimbra, Coimbra, Portugal

Diabetes Mellitus Type 2 (DM 2) has a high prevalence and appears as an important cause of morbidity and death in many countries of the western world. It has a multi-systemic scope and its chronic complications include retinopathy, neuropathy, cardiovascular disease and non-alcoholic fatty liver disease (NAFLD) . If the link between vision, neurological, cardiac complications and DM 2 has been clearly established, the association between DM 2 and NAFLD has been more recently recognized. In this work, multi-echo gradient-echo intra-voxel incoherent-motion imaging are applied to non-invasively identify staging biomarkers of NAFLD in the context of liver complications associated with Type II Diabetes Mellitus.

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