Abstract #1597
High Field Magnetic Resonance Angiogram of the Mouse Eye
Gangchea Lee 1 , Minjung Kim 2 , and Thomas Neuberger 1,3
1
Biomedical Engineering, Pennsylvania State
University, University Park, PA, United States,
2
Biology,
Pennsylvania State University, University Park, PA,
United States,
3
Huck
Institutes of the Life Sciences, Pennsylvania State
University, University Park, PA, United States
Retinal and choroidal vessels deliver the nutrition and
oxygen to maintain homeostasis for proper vision. The
damage on retina can cause a severe outcome of loss of
sight. In this study the feasibility generating a three
dimensional angiogram of the mouse eye using MRI was
explored. A magnetic field of 14 tesla and a dedicated
home built radiofrequency surface coil were used to
create a 30 um isotropic resolution angiogram of the
mouse eye. The results of this non-invasive study could
be used to investigate many ocular diseases, such as
diabetic retinopathy.
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