Meeting Banner
Abstract #1746

Cross-relaxation parameter quantification in cortical bone from repeated binomial excitations

Khaoula Bouazizi-Verdier 1 and Genevive Guillot 1

1 IR4M, UMR8081, CNRS, Univ. Paris-Sud, Orsay, France

Evidence of Magnetization Transfer was recently shown in cortical bone between collagen-bound water protons and collagen methylene protons, as well as a correlation between the amount of collagen methylene protons and mechanical properties. It is then important to quantify cross-relaxation parameters. Our purpose was to highlight Magnetization Transfer using inversion-recovery at two RF durations and repeated binomial excitation. The amount of collagen methylene protons assessed by simulation from the repeated binomial excitation data was in agreement with literature. A repeated binomial excitation can be easily integrated into a UTE sequence and should be used for quantitative Magnetization Transfer in vivo.

This abstract and the presentation materials are available to members only; a login is required.

Join Here