Meeting Banner
Abstract #1763

Quantitative Measurements of Amide Proton Transfer (APT) Signals and Tissue pH in Acute Ischemic Stroke

Dong-Hoon Lee 1 , Xiaoguang Liu 2 , Kai Zhang 1 , Yi Zhang 1 , Hye-Young Heo 1 , Wenxiao Li 1 , Raymond C. Koehler 2 , and Jinyuan Zhou 1

1 Division of MR Research, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States, 2 Department of Anesthesiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

APT imaging can be used to obtain tissue pH information. In this abstract, the quantitative measurements of APT signals and tissue pH in the acute ischemic stroke in rats were performed using extrapolated semi-solid magnetization transfer reference (EMR) signals. Our EMR approach may be helpful for more accurate APT pH quantification, and useful to understand and identify the characteristics of the ischemic stroke tissue.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords