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Abstract #1910

An EDB fibronectin specific contrast agent for molecular imaging of cancer metastasis

Zheng Han 1 , Zhuxian Zhou 1 , Maneesh Gujrati 1 , and Zheng-Rong Lu 1

1 Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States

This work uses ZD2-(HP-DO3A), a peptide-based targeting agent, for MRI molecular imaging of cancer metastasis. Accuracy and sensitivity of cancer metastasis imaging can be improved due to the sensitive targeting of this imaging agent to EDB fibronectin.

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