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Abstract #1934

Eight channel Tx/Rx RF coil array for 1 H/ 19 F MR of the Human Knee and Fluorinated Drugs at 7.0 T

Yiyi Ji 1 , Helmar Waiczies 1,2 , Lukas Winter 1 , Pavla Neumanova 1 , Daniela Hofmann 1 , Jan Rieger 1,2 , Ralf Mekle 3 , Sonia Waiczies 1 , and Thoralf Niendorf 1,4

1 Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrck Center for Molecular Medicine, Berlin, Germany, 2 MRI.TOOLS GmbH, Berlin, Germany, 3 Medical Physics, Physikalisch-Technische Bundesanstalt, Berlin, Germany, 4 Experimental and Clinical Research Center, a joint cooperation between the Charit Medical Faculty and the Max Delbrck Center, Berlin, Germany

The sensitivity limit for 19 F detection constitutes an impediment for translational research and clinical applications of in vivo 19 F MR. This limitation could be overcome by sensitivity gain at UHF. This work proposes a double-tuned 1 H/ 19 F Tx/Rx RF coil array tailored for knee imaging to examine the feasibility of human 1 H/ 19 F MR at 7.0 T. The suitability of the proposed approach for 19 F MR following topical application of a fluorinated drug is demonstrated.

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