Abstract #1934
Eight channel Tx/Rx RF coil array for 1 H/ 19 F MR of the Human Knee and Fluorinated Drugs at 7.0 T
Yiyi Ji 1 , Helmar Waiczies 1,2 , Lukas Winter 1 , Pavla Neumanova 1 , Daniela Hofmann 1 , Jan Rieger 1,2 , Ralf Mekle 3 , Sonia Waiczies 1 , and Thoralf Niendorf 1,4
1
Berlin Ultrahigh Field Facility (B.U.F.F.),
Max Delbrck Center for Molecular Medicine, Berlin,
Germany,
2
MRI.TOOLS
GmbH, Berlin, Germany,
3
Medical
Physics, Physikalisch-Technische Bundesanstalt, Berlin,
Germany,
4
Experimental
and Clinical Research Center, a joint cooperation
between the Charit Medical Faculty and the Max Delbrck
Center, Berlin, Germany
The sensitivity limit for
19
F
detection constitutes an impediment for translational
research and clinical applications of
in
vivo
19
F
MR. This limitation could be overcome by sensitivity
gain at UHF. This work proposes a double-tuned
1
H/
19
F
Tx/Rx RF coil array tailored for knee imaging to examine
the feasibility of human
1
H/
19
F
MR at 7.0 T. The suitability of the proposed approach
for
19
F
MR following topical application of a fluorinated drug
is demonstrated.
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