Determination of sources for evoked BOLD response under Hyperbaric Oxygen
Damon Philip Cardenas 1,2 , Eric R Muir 1,3 , Shiliang Huang 3 , and Timothy Q Duong 1,3
University of Texas Health Science Center at
San Antonio, San Antonio, Texas, United States,
Engineering, University of Texas San Antonio, San
Antonio, Texas, United States,
Imaging Institute, San Antonio, Texas, United States
Hyperbaric oxygen (HBO) therapy is used to treat a
number of ailments. Previously, during HBO at 3
atmospheres absolute fMRI studies, it was observed that
BOLD response to an evoked stimulus was not washed out
as a result of highly increased oxygen concentration.
Additional experiments were performed to evaluate the
potential contributions of stimulus-evoked inflow, spin
density, and electrical activity to BOLD fMRI responses
under HBO. CBF and BOLD fMRI of forepaw stimulation in
anesthetized rats was performed under HBO and compared
with normobaric air .
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