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Abstract #2034

Functional MRI of the main and accessory olfactory system in the whole rodent brain

Eric R. Muir 1 , Linlin Cong 1 , KC Biju 2 , William E. Rogers 1 , Robert A. Clark 3 , and Timothy Q. Duong 1

1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, United States, 2 Department of Medicine, University of Texas Health Science Center, San Antonio, TX, United States, 3 Institute for integration of Medicine & science and South Texas Veterans Health Care System, University of Texas Health Science Center, San Antonio, TX, United States

The olfactory system in most mammals consists of the main and the accessory olfactory systems. The main olfactory bulb receives input from the olfactory epithelium which senses volatile odors, while the accessory olfactory bulb receives input from the vomeronasal organ which senses pheromones. The accessory olfactory system plays an important role in rodents, but a single fMRI study investigating only the olfactory bulb of odor and pheromone stimulation has been performed to our knowledge. The aim of this study was to investigate fMRI responses to odor and urine (which contains pheromones) in the entire olfactory network of the mouse brain.

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