Abstract #2148
The Role of Collateral Circulation in Perfusion and Diffusion MRI after Stroke
Yu-Chieh Jill Kao 1,2 , Esteban A Oyarzabal 1 , Hua Zhang 3 , James E Faber 3 , and Yen-Yu Ian Shih 1
1
Neurology and BRIC, University of North
Carolina, Chapel Hill, NC, United States,
2
Imaging
Research Center, Taipei Medical University, Taipei,
Taipei, Taiwan,
3
Department
of Cell Biology and Physiology, University of North
Carolina, Chapel Hill, NC, United States
By using two genetically engineered mouse strains that
differ in collateral extent, the present study
demonstrated that collateral circulation significantly
suppresses the expansion of ischemic core, restores area
with cerebral blood flow deficit and reduces final
infarct size.
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