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Abstract #2164

Identifying Infarct Lesion using Diffusion Kurtosis Model with Multi-band EPI Sequence in Acute Ischemic Stroke Patients

Huan He 1 , Tianyi Qian 2 , Ni Liu 1 , Xingli Liu 1 , Zhongyan Wang 1 , Lu Su 1 , and Peiyi Gao 1

1 Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China, 2 MR Collaborations NE Asia, Siemens Healthcare, Beijing, China

The key to thrombolytic therapy in acute ischemic stroke is identifying the areas of infarct lesion in acute stage. By using a prototype simultaneous multi-slice accelerated (SMS) EPI sequence for DKI data recording, the total acquisition time could be cut down to 1/2~1/3 of standard EPI-based DKI without losing SNR. In the identification of the final infarct size in acute ischemic stroke, the volume measurements by SMS DKI in the acute-phase is more reliable than that of ADC, and the DKI data could be acquired in a reasonable time with the SMS EPI sequence.

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