Abstract #2165
Fast and robust lesion detection and assessment in acute ischaemic stroke patients from ADC and quantitative T2 mapping
Michael John Knight 1 , Bryony McGarry 1 , Harriet Rogers 1 , Joanne Robson 2 , Rose Bosnell 3 , Philip Clatworthy 1 , and Risto Kauppinen 1
1
School of experimental psychology,
University of Bristol, Bristol, avon, United Kingdom,
2
Southmead
Hospital, Bristol, avon, United Kingdom,
3
School
of clinical sciences, University of bristol, Bristol,
avon, United Kingdom
This work presents a simple, yet robust means for
identifying regions of acutely ischaemic tissue, with
minimal human intervention, from ADC mapping, and for
the assessment of that tissue based on quantitative T2
mapping in ischaemic stroke patients. Having identified
ADC lesions(s), we show using T2 mapping that within
ischaemia distinct tissue signatures with different
relaxation charateristics are separated. In particular,
whereas ADC and T2 are positively correlated in healthy
tissue, this is not the case in in the ischaemia, which
can act as a further restraint for distinguishing
between different tissue states and lesion types.
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