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Abstract #2165

Fast and robust lesion detection and assessment in acute ischaemic stroke patients from ADC and quantitative T2 mapping

Michael John Knight 1 , Bryony McGarry 1 , Harriet Rogers 1 , Joanne Robson 2 , Rose Bosnell 3 , Philip Clatworthy 1 , and Risto Kauppinen 1

1 School of experimental psychology, University of Bristol, Bristol, avon, United Kingdom, 2 Southmead Hospital, Bristol, avon, United Kingdom, 3 School of clinical sciences, University of bristol, Bristol, avon, United Kingdom

This work presents a simple, yet robust means for identifying regions of acutely ischaemic tissue, with minimal human intervention, from ADC mapping, and for the assessment of that tissue based on quantitative T2 mapping in ischaemic stroke patients. Having identified ADC lesions(s), we show using T2 mapping that within ischaemia distinct tissue signatures with different relaxation charateristics are separated. In particular, whereas ADC and T2 are positively correlated in healthy tissue, this is not the case in in the ischaemia, which can act as a further restraint for distinguishing between different tissue states and lesion types.

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