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Abstract #2206

Imaging dopamine autoreceptor activity using functional MRI as a novel technique in Parkinsons disease

Chiao-Chi V Chen 1 , Yi-Hua Hsu 1 , Chien-Yuan E Lin 2,3 , and Chen Chang 1

1 Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, 2 GE Healthcare, Taipei, Taiwan, 3 MR Advanced Application and Research Center, GE Healthcare, China

Imaging of dopamine autoreceptor activity is a brand new concept. We took advantage of our recently established noxiousness-evoked functional magnetic resonance imaging (fMRI) paradigm for developing such technique. This enables us to gain understanding about how D2 autoreceptor is affected in PD.

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